منابع مشابه
Commentary: Frailty and heterogeneity in epidemiological studies.
The paper by Aalen et al. is a timely discussion of an important topic. However, it conflates two concepts, frailty and heterogeneity, which are best kept apart. I would use the term frailty only when there is clear biological evidence that a fraction of the population is either exclusively at risk, or at vastly increased risk compared with the general population, of contracting a disease. An e...
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Frailty is a vulnerable situation among older adults which can lead to unfavorable health outcomes such as falls, mortality, functional decline and institutionalization. The increasing number of elderly people and low rate of mortality has necessitated the need for high-quality medical services for this aging population, and this has led to a high cost of geriatric health care. There exist a hu...
متن کاملCommentary: Frailty and cancer.
of Twin Registries (INTR): building a platform for international collaboration. Twin Res Hum Genet 2014;17:574–77. 3. McRae AF, Powell JE, Henders AK et al. Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome Biol 2014;15:R73. 4. Hopper JL. Disease-specific prospective family study cohorts enriched for familial risk. Epidemiol Perspect Innov 2011;8:2. 5...
متن کاملFrail or hale: Skeletal frailty indices in Medieval London skeletons
To broaden bioarchaeological applicability of skeletal frailty indices (SFIs) and increase sample size, we propose indices with fewer biomarkers (2-11 non-metric biomarkers) and compare these reduced biomarker SFIs to the original metric/non-metric 13-biomarker SFI. From the 2-11-biomarker SFIs, we choose the index with the fewest biomarkers (6-biomarker SFI), which still maintains the statisti...
متن کاملWho are the frail elderly?
To even the most casual observer, the elderly are a very heterogeneous population. Some individuals remain fit and active into their ninth or tenth decades, whilst others show evidence of infirmity during their early sixties in the absence of an acute physical illness. This dissociation of biological and chronological age represents a continuum bounded by, in the parlance of contemporary geront...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2020
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2020.05.073